Stem Cell Treatment for Acne Scars

Acne vulgaris is a common skin disease that has a very high incidence rate of 95% during adolescence and can later lead to permanent scars on the skin, namely acne scars. These scars, which are not treated effectively in the early stages or sometimes develop despite the right treatment, can create serious psychological effects in individuals and cause loss of self-confidence.

Especially today, current stem cell-supported autologous cell treatments applied within the Private Ankara Life Polyclinic under the leadership of experienced Doctor Fatma Yıldız offer a promising approach in treating acne scars both naturally and effectively.

Development of Acne Scars and Need for Treatment

During acne-related inflammation processes, healing problems such as fibroblast destruction, collagen loss and fibrosis are experienced. As a result, atrophic, hypertrophic or keloidal scar formations occur on the skin. Along with scars, color changes such as erythema, hyperpigmentation or hypopigmentation may also be observed.

In the treatment of such permanent skin changes; methods such as lasers, radiofrequency systems, chemical peels, subcision, microneedling have been used both alone and in combination, with varying success rates. However, today, patients are turning to more natural, minimally invasive methods with low risk of allergies and complications.

Stem Cell Supported Autologous Cell Therapies: The Most Natural Way of Regeneration

Autologous cell therapies are applications performed using natural biological materials obtained from the person's own tissue and containing no foreign substances.
The main autologous cell therapies are as follows:

Platelet-rich plasma (PRP) applications
Autologous fat tissue transfer (lipofilling)
Mesenchymal stem cell (MSC) applications
Fibroblast injections
These methods, especially applied by Doctor Fatma Yıldız at Private Ankara Life Polyclinic with personalized treatment plans, offer superior results in both skin rejuvenation and scar treatment.

Adipose Tissue (Fat Tissue) Transfer and Stromal Vascular Fraction (SVF)

Free fat tissue transplantation is an effective method for both eliminating volume loss and tissue regeneration in acne scars. It is known that 1 gram of fat tissue contains approximately 5000 adipose tissue stem cells (ADKH).

At Private Ankara Life Polyclinic, the fat tissue taken from the patient is purified with special processes and injected under the skin. Thanks to this injection:

Collagen production is triggered,
Neovascularization is provided,
Regeneration begins in the scar tissue.
Adipose tissue is applied in different forms such as macrofat, microfat, nanofat, SEFFI and SVF. SVF in particular is the form with the highest content of stem cells and very successful results have been obtained in acne scars.

Acne Scar Repair with Mesenchymal Stem Cell (MSC) Applications

Mesenchymal stem cells (MSC) are among the most important actors of regenerative medicine and are also used extensively in dermatological applications. MSCs:

Migrate to damaged tissues,
Renew tissue by differentiating into fibroblasts and keratinocytes,
Secrete anti-inflammatory cytokines,
Increase collagen and elastin synthesis,
Limit scar formation by reducing oxidative stress.
Scientific studies have shown that both adipose tissue-derived and bone marrow-derived MSC applications provide significant improvements in atrophic acne scars.

In stem cell treatments applied by Doctor Fatma Yıldız at Private Ankara Life Polyclinic, the most effective result is targeted by selecting MSC sources suitable for the patient's skin structure.

Autologous Fibroblast Culture and Injection

Fibroblasts are the main cells of the skin's connective tissue and are responsible for collagen production. Autologous fibroblast culture is based on the injection of fibroblasts that have been multiplied in a laboratory environment from a small skin biopsy taken from the patient.

In the treatment of acne scars:

New collagen formation is provided,
Extracellular matrix is ​​rearranged,
The elasticity and appearance of the scar tissue are improved.
The success of fibroblast treatment, especially in atrophic rolling type acne scars in the facial area, has been proven by scientific studies.
Private Ankara Life Polyclinic offers autologous fibroblast applications with the most advanced technology and GMP certified laboratory collaborations.

Supportive Treatments with PRP and Plasma Gel Applications

PRP is a platelet-rich plasma obtained from the patient's own blood. Cellular regeneration in the skin is supported thanks to the growth factors released from the alpha granules of platelets.

Plasma gel applications developed in recent years have become an effective supportive treatment method by providing intense fullness, especially in atrophic scars with volume loss.

At Private Ankara Life Polyclinic, PRP and plasma gel applications are combined with methods such as microneedling, laser and subcision to maximize treatment success.